Which moieties of nucleosides are involved in the formation of phosphodiester linkages present in dinucleotides? What does the word diester in the name of linkage indicate? Which acid is involved in the formation of this linkage?

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Solution

(i) 5' and 3' carbon atoms of pentose sugar.
(ii) Most probably the resemblance of with 2 ester $(- C O O)^{2 -}$ groups joined together.

(iii) Phosphoric acid $(H_{3} P O_{4})$
Nucleosides are joined together by phosphodiester linkage betwen 5' and 3' carbon atoms of pentose sugar and a dinucleotide with phosphoric acid $(H_{3} P O_{4})$ is formed

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