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Question

Which of the following antibiotics is active against fungus?

A
Streptomycin
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B
Polyenes
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C
Tetracycline
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D
Neomycin
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Solution

The correct option is B Polyenes
Polyenes work by destroying the cell membrane. It can bind to the sterols causing a hole in the membrane. This causes a hole in the cell thereby leaking the cell contents and death of the fungal cell.
Streptomycin is effective against tuberculosis, a bacterial disease.
Tetracycline is effective against a variety of bacterial infections such as gonorrhoea, urinary tract etc.
Neomycin is an antibiotic against many Gram positive and Gram negative bacteria.
Thus, the correct answer is option B.

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