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Question

Which of the following bonds are formed by action of DNA ligase?

A
Sugar-phosphate bond
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B
Phosphodiester bond
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C
Phosphate-phoshpate bond
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D
Both (1) and (2)
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Solution

The correct option is B Phosphodiester bond
The mechanism of DNA ligase is to form two covalent phosphodiester bonds between 3 hydroxyl end of one nucleotide(acceptor) with 5 phosphate end of another(donor).Two ATP molecules are consumed for each phosphodiester bond formation.
So, the correct answer is option B.

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