Which of the following causes chills and fever in malaria?
A
Hematin
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B
Haemozoin
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C
Schuffner's granules
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D
Hematocrit
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Solution
The correct option is B Haemozoin
Haemozoin is a disposal product formed from the digestion of blood by some blood-feeding parasites. These hematophagous organisms such as Malaria parasites (Plasmodium spp.), Rhodnius and Schistosoma digest haemoglobin and release high quantities of free heme, which is the non-protein component of hemoglobin. It is during this stage of infection that erythrocytes are destroyed and parasitic toxic waste is discharged, causing the characteristic symptoms of fever and chills in the victims.