Which of the following compounds is resistant to nucleophilic attack by hydroxyl ions?

Methyl acetate

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Acetonitrile

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Acetamide

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Diethyl ether

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Solution

The correct option is D Diethyl ether
Diethyl ether itself is a Lewis base and hence not attacked by hydroxyl ion whereas rest of the compounds contains an electrophilic carbon and gets attacked by nucleophiles.

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