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Question
Which of the following drugs prevents normal recycle of dopamine?
Which of the following drugs prevents normal recycle of dopamine?
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Solution
The correct option is B Cocaine
Cocaine is the principal drug obtained from cocoa plant. It increases the dopamine levels in the brain.
1. When cocaine reaches the synaptic cleft it attaches to the neurotransmitter re-uptake pump and blocks it completely.
2. As the impulse arrives at the synaptic knob, dopamine vesicle in the knob releases dopamine into the synaptic cleft.
3. Blockage of the re-uptake pump prevents normal recycle of dopamine which is needed to shut off the signal between neurons.
4. After repeated impulses, dopamine gets accumulated in the synaptic cleft.
5. Elevated concentration of dopamine increases the intensity of impulse due to continuous stimulation of postsynaptic neuron, resulting in the feeling of pleasure. Since cocaine increases the stimulation of neuron, it is known as a stimulant.
Cocaine is the principal drug obtained from cocoa plant. It increases the dopamine levels in the brain.
1. When cocaine reaches the synaptic cleft it attaches to the neurotransmitter re-uptake pump and blocks it completely.
2. As the impulse arrives at the synaptic knob, dopamine vesicle in the knob releases dopamine into the synaptic cleft.
3. Blockage of the re-uptake pump prevents normal recycle of dopamine which is needed to shut off the signal between neurons.
4. After repeated impulses, dopamine gets accumulated in the synaptic cleft.
5. Elevated concentration of dopamine increases the intensity of impulse due to continuous stimulation of postsynaptic neuron, resulting in the feeling of pleasure. Since cocaine increases the stimulation of neuron, it is known as a stimulant.
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