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Question
Which of the following immune responses is responsible for rejection of kidney graft?
Which of the following immune responses is responsible for rejection of kidney graft?
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Solution
The correct option is A Cell-mediated immune response
Graft refers to any living tissue (kidney, eye, heart, etc.) that is transplanted surgically. Tissue matching (MHC Matches) and blood group matching are essential before undertaking any graft/transplant as the immune system is able to differentiate ‘self’ and ‘nonself’ and the cell-mediated immune response can cause graft rejection.
Cytotoxic T cells play an important role in organ rejection. They are killer cells. They recognise the MHC complex (protein receptor) found on every cell and this helps to differentiate the foreign tissues from self, and there by attack the non self.
Patients have to take immuno–suppressants all his/her life to avoid infiltration of T cells but this also lowers their immunity.
Hence, the option a is correct.
The immune system's response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, is called inflammatory immune response. It removes injurious stimuli and initiates the healing process and hence, inflammation is a defense mechanism vital to health.
B cells mediated immunity is called humoral immunity. B cells produce circulating antibodies in blood that attack harmful foreign antigens.
In autoimmune responses, the immune system of the body produces antibodies against its own cells (self-cells).
Graft refers to any living tissue (kidney, eye, heart, etc.) that is transplanted surgically. Tissue matching (MHC Matches) and blood group matching are essential before undertaking any graft/transplant as the immune system is able to differentiate ‘self’ and ‘nonself’ and the cell-mediated immune response can cause graft rejection.
Cytotoxic T cells play an important role in organ rejection. They are killer cells. They recognise the MHC complex (protein receptor) found on every cell and this helps to differentiate the foreign tissues from self, and there by attack the non self.
Patients have to take immuno–suppressants all his/her life to avoid infiltration of T cells but this also lowers their immunity.
Hence, the option a is correct.
The immune system's response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, is called inflammatory immune response. It removes injurious stimuli and initiates the healing process and hence, inflammation is a defense mechanism vital to health.
B cells mediated immunity is called humoral immunity. B cells produce circulating antibodies in blood that attack harmful foreign antigens.
In autoimmune responses, the immune system of the body produces antibodies against its own cells (self-cells).
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