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Question

Which of the following immunoglobulins is responsible for allergic responses on contact with antigens?

A
IgA
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B
IgE
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C
IgM
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D
Both a and c
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Solution

The correct option is B IgE
Immunoglobulins are proteins that are present in the body fluids to provide immunity against specific antigens (foreign substances that can trigger production of antibodies and immunological cells).

Five different classes of antibodies are produced in the body, namely, IgA, IgG, IgE, IgM and IgD.

IgE is mainly found in the mucous membranes, skin and lungs. It triggers allergic responses on coming in contact with antigens.

IgM is the first antibody produced in primary immune response.
IgA is the major immunoglobulin in colostrum.
IgG antibody can cross placenta and provide immunity to the foetus.
So, the correct answer is IgE.

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