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Question

Which of the following is a biological uncoupler of oxidative phosphorylation?

A
Thermogenin.
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B
2, 4-Dichlorophenoxyacetic acid.
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C
2, 4-Dinitrophenol.
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D
Ethylene diaminotetra-acetic acid.
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Solution

The correct option is A Thermogenin.
Brown adipose tissue is rich in mitochondria, containing an uncoupling protein (thermogenin) that uncouples oxidation and phosphorylation of adenosine diphosphate, reduces ATP production, and consequently enhances thermogenesis.
So the correct option is 'Thermogenin'.

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