Which of the following is a biological uncoupler of oxidative phosphorylation?
A
Thermogenin.
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B
2, 4-Dichlorophenoxyacetic acid.
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C
2, 4-Dinitrophenol.
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D
Ethylene diaminotetra-acetic acid.
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Solution
The correct option is A Thermogenin. Brown adipose tissue is rich in mitochondria, containing an uncoupling protein (thermogenin) that uncouples oxidation and phosphorylation of adenosine diphosphate, reduces ATP production, and consequently enhances thermogenesis.