Question

Which of the following is a major substrate for synthesis of fats?

• A. Acetyl- CoA
• B. Pyruvate
• C. Glycogen
• D. None of the above

Answer 1

Answer: (A)

Acetyl- CoA

Fatty acids are components of the phospholipids that make up the bulk of the lipid bilayers of all cellular membranes. It is synthesized by cytosolic acetyl-CoA through carboxylation by acetyl-CoA carboxylase into malonyl CoA. This conversion occurs primarily in the liver, adipose tissue and lactating mammary glands, where the fatty acids are combined with glycerol to form triglycerides

So, the correct answer is option A.