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Question
Which of the following is correct for oxygen transport ?
Which of the following is correct for oxygen transport ?
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Solution
The correct option is D Both B and C
- For purposes of discussing oxygen transport by the blood, we will consider blood to be composed of two phases: plasma and red blood cells (RBCs). Oxygen is carried in the blood in two forms: (1) dissolved in plasma and RBC water (about 2% of the total) and (2) reversibly bound to hemoglobin (about 98% of the total). At physiological PO2, only a small amount of oxygen is dissolved in plasma since oxygen has such a low solubility. At elevated PO2 (breathing 100 % oxygen or during hyperbaric oxygenation), however, the physically dissolved form of oxygen can become significant. Henry's law states that the amount of oxygen dissolved in plasma is directly proportional to PO2: [O2] = α PO2, where α = 0.003 ml O2 (100 ml plasma)−1 mm Hg−1. Thus, at a PO2 of 100 mm Hg (a typical value for arterial blood), 100 ml of plasma contains 0.3 ml O2 (or 0.3 vol%).
- Some of the carbon dioxide is transported dissolved in the plasma. Some carbon dioxide is transported as carbaminohemoglobin. However, most carbon dioxide is transported as bicarbonate. As blood flows through the tissues, carbon dioxide diffuses into red blood cells, where it is converted into bicarbonate.
- Carbon dioxide is transported in the blood from the tissue to the lungs in three ways:1(i) dissolved in a solution; (ii) buffered with water as carbonic acid; (iii) bound to proteins, particularly hemoglobin. Approximately 75% of carbon dioxide transport in the red blood cell and 25% in the plasma. The relatively small amount in plasma attributable to a lack of carbonic anhydrase plasma so an association with water is slow; plasma plays little role in buffering and combination with plasma proteins is poor.
So, the correct answer is 'Both B and C'.
- For purposes of discussing oxygen transport by the blood, we will consider blood to be composed of two phases: plasma and red blood cells (RBCs). Oxygen is carried in the blood in two forms: (1) dissolved in plasma and RBC water (about 2% of the total) and (2) reversibly bound to hemoglobin (about 98% of the total). At physiological PO2, only a small amount of oxygen is dissolved in plasma since oxygen has such a low solubility. At elevated PO2 (breathing 100 % oxygen or during hyperbaric oxygenation), however, the physically dissolved form of oxygen can become significant. Henry's law states that the amount of oxygen dissolved in plasma is directly proportional to PO2: [O2] = α PO2, where α = 0.003 ml O2 (100 ml plasma)−1 mm Hg−1. Thus, at a PO2 of 100 mm Hg (a typical value for arterial blood), 100 ml of plasma contains 0.3 ml O2 (or 0.3 vol%).
- Some of the carbon dioxide is transported dissolved in the plasma. Some carbon dioxide is transported as carbaminohemoglobin. However, most carbon dioxide is transported as bicarbonate. As blood flows through the tissues, carbon dioxide diffuses into red blood cells, where it is converted into bicarbonate.
- Carbon dioxide is transported in the blood from the tissue to the lungs in three ways:1(i) dissolved in a solution; (ii) buffered with water as carbonic acid; (iii) bound to proteins, particularly hemoglobin. Approximately 75% of carbon dioxide transport in the red blood cell and 25% in the plasma. The relatively small amount in plasma attributable to a lack of carbonic anhydrase plasma so an association with water is slow; plasma plays little role in buffering and combination with plasma proteins is poor.
So, the correct answer is 'Both B and C'.
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