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Question

Which of the following is most effective chemical mutagen?

A
Methane
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B
Guanine
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C
N-ethyl-N-nitrosourea
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D
Caffeine
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Solution

The correct option is C N-ethyl-N-nitrosourea
A. Methane is component of various chemical mutagens such ethyl methane sulphanate .
B. Guanine is a pyrimidine and one of four nucleotides found in nucleic acids DNA and RNA.
C. N-ethyl-N-nitrosurea is a potent mutagen and is an alkylating agent which causes transitions and transversions mutations in DNA.
D. Caffeine is an alkaloid found in coffee. It is a stimulant of central nervous system.
Hence, most effective chemical mutagen is N-ethyl-N-nitrosurea. So, the correct answer is 'N-ethyl-N-nitrosourea'.

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