Question

Which of the following is not characteristic of the early stages of a localized inflammatory response?

• A. Increased permeability of capillaries
• B. Attack by cytotoxic T-cells
• C. Release of histamine
• D. Dilatation of blood vessels

Answer 1

Answer: (B)

Attack by cytotoxic T-cells

Inflammation is a very prominent response to TNF-α. There are four typical signs of inflammation, erythema (redness), heat, swelling, and pain. These are a consequence of increased blood flow and capillary permeability, the influx of phagocytic cells, and tissue damage. Increased blood flow is caused by constriction of the capillaries that carry blood away from the infected area, and leads to engorgement of the capillary network. Erythema and an increase in tissue temperature accompany capillary constriction. In addition, the permeability of capillaries increases, allowing cells and fluid to leave and enter the surrounding tissue. These fluids have a higher protein content than the fluids normally found in tissues, causing swelling.

So, the correct option is 'Option B'.