Question

Which of the following is the best evidence for the lock and key hypothesis of enzyme action?

• A. All isolated enzymes have been identified as proteins
• B. Enzymes determine the direction of a reaction
• C. Enzymes are found in living organisms and speed up certain reactions
• D. Compounds similar in structure to the substrate inhibit the reaction

Answer 1

The correct option is D Compounds similar in structure to the substrate inhibit the reaction

According to the lock and key mechanism only specific shapes of substrates that fixes into an enzyme is catalyzed. Compounds similar in structure to the substrate inhibit the reaction and is the best evidence for the lock and key hypothesis of enzyme action.

So, the correct option is 'Compound similar in structure to the substrate inhibits the reaction'.