Question

Which of the following reaction/reactions does not involve Hoffmann bromamide degradation?

• A.

  

• B.

  

• C.

  

• D.

  

Answer 1

The correct option is D

Hoffmann bromamide degradation:

• The Hoffmann bromamide reaction process typically involves attacking the amide with an alkali as a strong base, which results in deprotonation and the production of an anion.
• A primary amide is converted to a primary amine with one less carbon atom using this process.
• The primary amide is heated with a combination of a halogen (chlorine or bromine), a strong base and water to achieve this.

Explanation of the correct option D:

.

Explanation of the incorrect options A, B, and C:

This reaction does not involve Hoffmann bromamide degradation.

Hence, option D is the answer.