Which of the following results in stabilizing selection in a population?
A
Founder effect
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B
Heterozygote advantage
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C
Population bottleneck
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D
Random mating
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E
Reproductive isolation
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Solution
The correct option is B Heterozygote advantage
Stabilizing selection in a population acts against extremes and favors intermediate phenotypes. This refers often to heterozygous advantage, in which natural selection favors the heterozygote because it possesses benefits that homozygotes lack. In other words, A heterozygote advantage (heterozygous advantage) describes the case in which the heterozygote genotype has a higher relative fitness than either the homozygote dominant or homozygote recessive genotype. For example, people homozygous recessive for sickle cell anemia, meaning they have the disease, are also immune to malaria, a disease common in Africa, where sickle cell originated. Those heterozygous for the trait show no symptoms of sickle cell, but they are immune to malaria, greatly benefitting the heterozygote.