The correct option is B A+ boy and A− girl
When a Rh-negative mother is impregnated by a Rh-positive father and is carrying an Rh-positive baby, the foetus Rh antigens will be perceived as foreign invaders in mother's body. It can initiate the protective mechanism that can end up harming the child during second pregnancy and is called as erythroblastosis foetalis. So, A+ boy and A− girl should be avoided in biological marriages. The correct answer is B.