Question

Which of the following statements is not correct?

• A. The proinsulin has an extra peptide called C-peptide
• B. The functional insulin has A and B chains linked together by hydrogen bonds
• C. Genetically engineered insulin is produced in E-coli
• D. In man insulin is synthesised as a proinsulin

Answer 1

The correct option is B The functional insulin has A and B chains linked together by hydrogen bonds

• The genetically engineered insulin is produced with the help of E. coli.
• The insulin that is synthesized is the inactive form called proinsulin.
• The proinsulin having three chains (A, B, and C) connected together.
• The C-peptide chain is an extra peptide that gets removed when formation of active form of Insulin takes place.
• The active insulin has two peptide chain (A and B) linked with Disulfide bonds.

Thus, the incorrect statement given is (B).