Which of the following T-cells are destroyed by HIV?
A
Cytotoxic T-cells
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B
Killer T-cells
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C
Suppressor T-cells
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D
Helper T-cells
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Solution
The correct option is C Helper T-cells
HIV infects vital cells in the human immune system such as helper T cells (specifically T- CD4 lymphocytes), macrophages and dendritic cells.
The T helper cells are a type of T-cell that plays an important role in the immune system, particularly in the adaptive immune system. They help the activity of other immune cells by releasing T cell cytokines.
By viral replication, T-helper cells get damaged and gradually reduce in number.
Towards the end of an HIV infection, the number of functional T- CD4lymphocytes falls, which leads to the symptomatic stage of infection called AIDS (Acquired Immune Deficiency Syndrome).