Which one of palindromic base sequences in DNA can be easily cut at about the middle by some particular restriction enzyme ?
A
5'______ GAATTC ______3' 3'______ CTTAAG ______5'
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B
5'______ CACGTA ______3' 3'______ CTCAGT ______5'
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C
5'______ CGTTCG ______3' 3'______ ATGGTA ______5'
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D
5'______ GATATG ______3' 3'______ CTACTA ______5'
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Solution
The correct option is B 5'______ GAATTC ______3' 3'______ CTTAAG ______5' The palindromic sequence is a nucleic acid sequence (DNA or RNA) which is read same from 5' to 3' on one strand and 5' to 3' on its complementary strand and hence can be cut easily. The sequence in option A is read same from 5' to 3' on one strand and 5' to 3' on its complementary strand (5' GAATTC 3'). The other sequences are not examples of palindromic sequences.