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Question

Which one of the following is an incorrect statement about mitochondrial ETC and oxidative phosphorylation?

A
Enzyme complex I accepts electrons and H+ from NADH and FADH2
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B
Passage of protons through the channel is coupled to the catalytic site of the F0F1 particle for ATP production
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C
Cytochrome-c is a mobile protein attached on the outer surface of the inner membrane
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D
6 H+ ions pass through F0 from intermembrane space to the matrix down the electrochemical proton gradient to produce 3 ATP molecules
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Solution

The correct option is A Enzyme complex I accepts electrons and H+ from NADH and FADH2
Electron transport chain is responsible for oxidative phosphorylation in which e and H+ of NADH are accepted by complex I and then the electrons move through different carriers. 6 protons are pumped in intermembranous space which later diffuse to the matrix through F0F1 (ATP synthase) to form 3 ATP. FADH2 always enters in ETS through complex II. Cytochromes bc1, c,and aa3 are arranged in ETS according to the order of redox potential. Cytochrome c is a mobile electron carrier.

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