Which one of the following is used as a vector for cloning of genes into higher organisms?
A
Retrovirus
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B
Baculo virus
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C
Salmonella typhimurium
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D
Rhizopus nigricans
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Solution
The correct option is A Retrovirus
A retrovirus is a single-stranded RNA virus that stores its nucleic acid in the form of an mRNA genome and targets a host cell as an obligate parasite.
Once inside the host cell cytoplasm, the virus uses its own reverse transcriptase enzyme to produce DNA from its RNA genome, the reverse of the usual pattern.
Thus, retroviruses function differently - their RNA is reverse-transcribed into DNA, which is integrated into the host cell's genome, and then undergoes the usual transcription and translational processes to express the genes carried by the virus.
These are used as a vector for the cloning of genes into higher animals.