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Question

Which one of the following is used as vector for cloning genes into higher organisms?

A
Salmonella typhimurium
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B
Rhizopus-nigricans
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C
Retrovirus
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D
Baculovirus
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Solution

The correct option is A Retrovirus
  • Retroviruses are RNA containing viruses that replicate itself by first reverse-coding its genes into the DNA of the cells it infects. Once transformed from RNA to DNA, the viral DNA can be integrated into the genome of the infected cells.
  • They are in animals have the ability to transform normal cells into cancerous cells. Scientists have transformed these pathogens into useful vectors for delivering genes of interest to humans.
  • Retroviruses have been disarmed and are now used to deliver desirable genes into animal cells. So, once a gene or a DNA fragment has been ligated into a suitable retroviral vector it is transferred into a bacterial, plant or animal host (where it multiplies).
So the correct answer is option C.

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