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Question

Which part of nephron in human kidney is associated with active transport of Na+?

A
Bowman's capsule
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B
Convoluted part
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C
Collecting tubule
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D
Neck
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Solution

The correct option is B Convoluted part
The proximal tubule which is the portion of the duct system of the nephron of the kidney leads from Bowman's capsule to the loop of Henle. The proximal tubule regulates the pH of the filtrate by exchanging hydrogen ions in the interstitium for bicarbonate ions in the filtrate. It also secretes organic acids, such as creatinine and other bases, into the filtrate. Fluid in the filtrate entering the proximal convoluted tubule is reabsorbed into the peritubular capillaries. This is driven by sodium transport from the lumen into the blood by the Na+/K+ ATPase in the basolateral membrane of the epithelial cells. Sodium reabsorption is primarily driven by this P-type ATPase. This is the most important transport mechanism in the PCT. Thus, option B is correct and other options are wrong.

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