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Question

Which stage of plasmodium tears the hepatocytes?

A
Sporozoites
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B
Merozoites
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C
Oocyst
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D
None of these
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Solution

The correct option is B Merozoites
Plasmodium species exhibit three life-cycle stages—gametocytes, sporozoites, and merozoites. Gametocytes within a mosquito develop into sporozoites. The sporozoites are transmitted via the saliva of a feeding mosquito to the human bloodstream. From there they enter liver parenchyma cells, where they divide and form merozoites. The merozoites are released into the bloodstream and infect red blood cells. Rapid division of the merozoites results in the destruction of the red blood cells, and the newly multiplied merozoites then infect new red blood cells. Some merozoites may develop into gametocytes, which can be ingested by a feeding mosquito, starting the life cycle over again. The red blood cells destroyed by the merozoites liberate toxins that cause the periodic chill-and-fever cycles that are the typical symptoms of malaria. So, the correct answer is B.

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