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Question

While assigning R, S configuration the correct order of priority of groups attached to chiral carbon atom is :

A
CONH2>COCH3>CH2OH>CHO
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B
CONH2>COCH3>CHO>CH2OH
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C
COCH3>CONH2>CHO>CH2OH
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D
CHO>CH2OH>COCH3>CONH2
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Solution

The correct option is D CONH2>COCH3>CHO>CH2OH
While assigning R, S configuration the correct order of priority of groups attached to chiral carbon atom is CONH2>COCH3>CHO>CH2OH
Atomic having higher atomic number has higher priority.
The decreasing order of atomic numbers is O>N>C>H
In CONH2 group, the C atom is attached to 2 O atoms and one N atom.
In COCH3 group, the C atom is attached to 2 O atoms and one C atom.
In CHO group, the C atom is attached to 2 O atoms and one H atom.
In CH2OH group, the C atom is attached to 2 H atoms and one O atom.

Option B is correct.

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