The correct option is B Edward Jenner
One peculiar observation by Edward Jenner was that milkmaids who were affected by cowpox did not catch smallpox. Jenner took fluid from a cowpox blister and scratched it into the skin of an eight-year-old boy. A single blister rose up on the spot, but he soon recovered. Jenner inoculated the boy again, this time with smallpox matter, and no disease developed. This finding led to the discovery of the smallpox vaccine.