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Question

Who synthesised the first artificial gene?

A
Morgan
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B
Mendel
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C
Khorana
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D
Nirenberg
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Solution

The correct option is C Khorana
Morgan
Morgan established the chromosomal theory of heredity via his experiments on the fruit fly or Drosophila melanogaster.

Nirenberg
Nirenberg helped in cracking the genetic code for different amino acids by performing protein synthesis in a cell free medium.

Khorana
Har Gobind Khorana developed a chemical method that was used in synthesising RNA molecules with defined combinations of bases [homopolymers and copolymers]. Thus he artificially synthesised genes on an RNA strand which could be translated into polypeptides.

Mendel
Mendel performed artificial crossing experiments on different varieties of Pisum sativum to understand the inheritance of different traits and based on his observations he laid down the three laws of inheritance.

Final answer
(C) Khorana

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