Question

Why allosteric inhibition is called feedback inhibition ? Explain

Answer 1

In allosteric, the inhibitor is binding at a site other than the active site, and changing the enzyme in some way to make it inactive. Feedback inhibition is usually accomplished through “allosteric site”. In feedback inhibition, binding of the end product to the allosteric site slows down or stops the enzyme’s activity so that little or no new end product is produced. When levels of the end product drop, the enzyme will encounter fewer particles of the end product and its activity will increase again. The result of feedback inhibition is this allows them to adjust their rate of reaction depending on how much of their end product is needed and prevent their end product from building up to dangerous levels. That's why allosteric inhibition is called as feedback inhibition.