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Question

Why is protein digesting enzymes in the stomach released as inactive enzymes or zymogens.

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Solution

Zymogens

Digestive enzymes are released in inactive forms called zymogens. This is necessary to prevent the digestive enzymes from digesting the cells that produce them. In a zymogen, part of the protein blocks the active site of the enzyme. Cleaving off this peptide activates the enzyme.


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