wiz-icon
MyQuestionIcon
MyQuestionIcon
1
You visited us 1 times! Enjoying our articles? Unlock Full Access!
Question

Widal test is performed for

A
Malarial fever
No worries! We‘ve got your back. Try BYJU‘S free classes today!
B
Cholera
No worries! We‘ve got your back. Try BYJU‘S free classes today!
C
Typhoid fever
Right on! Give the BNAT exam to get a 100% scholarship for BYJUS courses
D
Dengue fever
No worries! We‘ve got your back. Try BYJU‘S free classes today!
Open in App
Solution

The correct option is C Typhoid fever

Widal test is an agglutination test, which detects the presence of serum agglutinins (H and O) in patient's serum with typhoid and paratyphoid fever. It was developed by Georges Fernand Widal in 1896. Bacterial suspension, which carry antigen will agglutinate on exposure to antibodies to Salmonella organisms. Patients’ suffering from enteric fever would possess antibodies in their sera, which can react and agglutinate serial doubling dilutions of killed, coloured Salmonella antigens in a agglutination test.

The main principle of Widal test is that if homologous antibody is present in patients serum, it will react with respective antigen in the reagent and gives visible clumping on the test card and agglutination in the tube. The antigens used in the test are “H” and “O” antigens of Salmonella typhi and “H” antigen of S. paratyphi. The paratyphoid “O” antigen are not employed as they cross react with typhoid “O” antigen due to the sharing of factor 12. “O” antigen is a somatic antigen and “H” antigen is flagellar antigen.


flag
Suggest Corrections
thumbs-up
0
Join BYJU'S Learning Program
similar_icon
Related Videos
thumbnail
lock
Skeletal System
BIOLOGY
Watch in App
Join BYJU'S Learning Program
CrossIcon