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Question

Will there be any change in the function of the red blood cells if they are changed into spindle shape?

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Solution

Normally RBC are biconcave in shape in order to increase the surface area for oxygenation and deoxygenation ,

Biconcavity infers most stable structure of RBC with maximum surface area

If its shape is changed for any reasons it will either lose or will have reduced its oxygenation and deoxygenation capacity

Its shape changes under following conditions

1.iron deficiency anemia(RBC becomes small)

2. Vitamin B12 and folic acid deficiency(increased size of RBC)

3.spherocytosis(RBC becomes spherical)

4. Stomatocytosis(rbc becomes like stoma)

5.sicle cell anaemia(RBC becomes sickle cshaped)

These are some common disease and conditions for change in RBC shapes .


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