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Question

With the Bohr effect, more oxygen is released because a(n) ________.


A

decrease in pH (acidosis) strengthens the hemoglobin-oxygen bond

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B

decrease in pH (acidosis) weakens the hemoglobin-oxygen bond

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C

increase in pH (alkalosis) strengthens the hemoglobin-oxygen bond

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D

increase in pH (alkalosis) weakens the hemoglobin-oxygen bond

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Solution

The correct option is B

decrease in pH (acidosis) weakens the hemoglobin-oxygen bond


The Bohr effect is a physiological phenomenon first described in 1904 by the Danish physiologist Christian Bohr, stating that haemoglobin's oxygen binding affinity is inversely related both to acidity and to the concentration of carbon dioxide.

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