Role of HCl

Q. How does pepsinogen change into its active form?

Q.

State whether the following statement is true or false. If false, rewrite the sentence by changing the incorrect word/words.
Enteropeptidase activates pepsinogen into pepsin.

1. True
2. False

Q. What is the use of HCl secreted by the stomach?

1. Converts pepsin to pepsinogen
2. Does not help in the digestion of protein
3. Converts pepsinogen to pepsin
4. Helps in the survival of bacteria

Q. The optimal pH for the action of pepsin is

1. 1.8
2. 6.8
3. 7
4. 7.8

Q. Assertion- pH of the stomach is more than 7.
Reason- Stomach contains oxyntic cells that produce HCl.

1. Both assertion and reason are true and the reason is the correct explanation of the assertion
2. Both assertion and reason are true but the reason is not the correct explanation of the assertion
3. The assertion is false but the reason is true
4. Both assertion and reason are false

Q.

Identify the steps (denoted by numerals) in physiology of digestion in stomach.

i).Food $\stackrel{HCl}{\underset{KillsBacteria}{⟶}}$ Chyme

ii).Pepsinogen Prorennin $\stackrel{HCl}{\underset{Activation}{⟶}}$ Pepsin Rennin

iii).Proteins $\stackrel{Pepsin}{⟶}$ Proteases Peptones

iv).Milk Casein $\stackrel{Rennin}{⟶}$Para casein $\stackrel{Calcium}{⟶}$ Calcium paracaseinate

1. i). Acidification ii). Activation by HCl iii). Digestion iv). Digestion of Milk in infants
2. i). Deactivation ii). Acidification iii). Activation by HCl iv). Digestion
3. i). Activation by HCl ii). Digestion iii). Deactivation iv). Acidification
4. i). Digestion ii). Deactivation iii). Acidification iv). Activation by HCl

Q. What would happen if HCl was not secreted in the stomach?

Q. What will happen if the secretion of parietal cells of the gastric glands is blocked with an inhibitor?

1. Gastric juice will be deficient in chymosin
2. Gastric juice will be deficient in pepsinogen
3. In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin
4. Enterokinase will not be released from the doudenal mucosa and so, trypsinogen is not converted to trypsin

Q.

What would happen if HCl were not secreted in the stomach?