Mutation

Q.

What is point mutation? Give an example.

Q.

What are types of mutations?

Q. What is point mutation? Give examples.

Q.

Which Type of Mutation Causes the Most Damage?

Q.

What is an example of a transversion mutation?

Q.

What are the 2 types of mutation?

Q. A gene whose expression helps to identify transformed cell is known as

1. Plasmid
2. Selectable marker
3. Vector
4. Structural gene

Q. Which of the following is an example of a pleiotropy?

1. Haemophilia
2. Thalassemia
3. Sickle cell anemia
4. Colour blindness

Q.

Can point mutations cause frame shift?

Q.

What is an example of neutral mutation?

Q. Gene expression can be controlled with the help of RNA. Explain the method with an example

Q. Recognise the figure and find out the correct matching.

1. $c-\text{Glu},d-\text{Val},a-\text{normal~Hb~(A)~gene},b-\text{sickle~cell~Hb~(S)~gene}$
2. $c-\text{Glu},d-\text{Val},b-\text{normal~Hb~(A)~gene},a-\text{sickle~cell~Hb~(S)~gene}$
3. $d-\text{Glu},c-\text{Val},a-\text{normal~Hb~(A)~gene},b-\text{sickle~cell~Hb~(S)~gene}$
4. $c-\text{Glu},d-\text{Val},b-\text{normal~Hb~(A)~gene},a-\text{sickle~cell~Hb~(S)~gene}$

Q.

Which of the given disorders can be seen in an individual, when the mutation includes the substitution of a purine by pyrimidine?

1. Transversion

2. Transition

3. Tautomerisation

4. Frameshift mutation

Q. What are Point Mutations? Give one example of Point Mutations.

Q. Choose the incorrect statement regarding Hardy - Weinberg principle.

1. Allele frequencies in a population are stable and constant from generation to generation

2. Sum total of all the allelic frequencies in a population is 1

3. Variation due to genetic drift results in changed frequency of genes and alleles in future generations

4. Genetic recombination helps in maintaining the Hardy - Weinberg equilibrium

Q. Variation in gene frequencies within populations can occur by chance rather than by natural selection. The is referred to as :-

1. Random mating
2. Genetic drift
3. Genetic flow
4. Genetic load

Q. Mutations are considered directionless because

1. these occur in all organisms of a species
2. these can be useful, harmful or neutral
3. these occur at a specific time
4. these can cause evolutionary change in a single generation

Q. AIDS is caused due to a ___(i)______that has RNA as the genetic material which undergoes ___(ii)____to form____(iii)______ inside the host cells.

1. (i)-bacterium, (ii)-transcription, (iii)-DNA
2. (i)-virus, (ii)-reverse transcription, (iii)-DNA
3. (i)-bacterium, (ii)-reverse transcription, (iii)-DNA
4. (i)-virus, (ii)-reverse transcription, (iii)-RNA

Q.

Which of the following is most commonly used for creation of genetic variation?

1. Mutation

2. Polyploidy

3. Genetic engineering

4. Hybridisation

Q.

What are the two types of mutation?

Q. Sickle cell anaemia is

1. caused by substitution of valine by glutamic acid in the beta globin chain of haemoglobin
2. caused by a change in a single base pair of DNA
3. characterised by elongated sickle like RBCs with a nucleus
4. an autosomal linked dominant trait

Q.

What kind of gene mutations are possible?

Q.

How do mutations affect traits?

Q.

What is point mutation? Give one example.

Q.

Which is a frameshift mutation?

Q.

What are silent point mutations?

Q. If there are two pathogenic viruses, one with DNA and other with RNA, which would mutate faster? And why?

Q. Ti plasmid transforms cells of

1. Bacteria
2. Plants
3. Fungi
4. Animals

Q. Match the following of column I with that of column II.

Column I	Column II
i. Mutation	p. Random allele frequency fluctuation
ii. Genetic recombination	q. Migration of genes/alleles from one population to another
iii. Gene migration	r. Occurrence of new genetic combination during sexual reproduction
iv. Genetic drift	s. Sudden change in DNA sequence

1. i – p, ii – q, iii –r, iv – s
2. i – s, ii – r, iii – q, iv – p
3. i – s, ii – r, iii – p, iv – q
4. i – s, ii – q, iii – r, iv – p

Q. Genetic code consists of

1. 4 codons, each with two nucleotides
2. 16 codons, each with four nucleotides
3. 64 codons, each with two nucleotides
4. 64 codons, each with three nucleotides