Question

A hereditary disease which is never passed on from father to son is

• A. X-chromosomal linked disease
• B. Autosomal linked disease
• C. Y-chromosomal linked disease
• D. None of the above

Answer 1

The correct option is A X-chromosomal linked disease

X chromosomes linked diseases are inherited with inheritance of X chromosome. Since father transmits its X chromosome to the daughters, not to son, X linked diseases cannot be passed from a father to son. This makes option A correct. Y chromosome linked diseases are the one genes for which are present on Y chromosome specific loci only. Since father transmits Y chromosome to son, these diseases are transmitted from father to son with Y chromosome. This makes option C incorrect. Option B is incorrect as inheritance of autosomal linked disease is independent on sex of individuals and thus, is not affected by inheritance of sex chromosomes.