Question

Aminoacylation of tRNA is essential for

• A. Replication of RNA
• B. Formation of peptide bond
• C. Splicing
• D. Initiation of transcription
• E. Termination

Answer 1

The correct option is B Formation of peptide bond

Aminoacylation is required for the formation of the peptide bond. For the synthesis of proteins, three steps are required, i.e. initiation, elongation and termination.
For the initiation to take place, the ribosome first binds to mRNA at the start codon (AUG) that is always recognised by the initiator tRNA.
As the formation of peptide bonds require energy and in the first phase, the amino acids are activated in the presence of ATP and linked to their tRNA also known as charging of tRNA or aminoacylation of tRNA.