Question

Explain aminoacylation of tRNA.

Answer 1

Activation of amino acids and formation of AA-tRNA complex is the first step of translation. In presence of an enzyme tRNA synthetase, the amino acid (AA) molecule is activated and then each amino acid is attached to the specific tRNAmolecule at 3' / CCA end to form aminoacyl- tRNA complex. The reaction needs ATP. This process is called charging of tRNA or aminoacylation of tRNA.