Question

Arrange the steps in signal transduction of steroid hormones across the cell in the correct order
I. Interaction of complex with DNA
II. Formation of hormone-receptor complex
III. Physiological responses
IV. Binding of hormone to the intracellular receptor
V. Biochemical actions

• A. II $\to$ IV $\to$ I $\to$ III $\to$ V
• B. IV $\to$ I $\to$ II $\to$ V $\to$ III
• C. IV $\to$ II $\to$ I $\to$ V $\to$ III
• D. II $\to$ IV $\to$ III $\to$ I $\to$ V

Answer 1

The correct option is C IV $\to$ II $\to$ I $\to$ V $\to$ III

The initial step in the signal transduction process is the binding of the hormone with the intracellular receptor. This binding results in the formation of the hormone-receptor complex, which, in turn goes and interacts with the DNA molecules. This elicits biochemical reactions which, in turn, results in the generation of the required physiological responses in the body.