Assertion :Competitive inhibitors compete with the natural substrate for their attachment on the active sites of enzymes. Reason: In competitive inhibition, inhibitor binds to allosteric site of the enzyme.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

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Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

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Assertion is correct but Reason is incorrect

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Both Assertion and Reason are incorrect

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Solution

The correct option is C Assertion is correct but Reason is incorrect
Drugs compete with the natural substrate for their attachment on the active sites of enzymes. Such drugs are called competitive inhibitors.
Some drugs do not bind to the enzyme’s active site. These bind to a different site of enzyme which is called allosteric site. This binding of inhibitor at allosteric site changes the shape of the active site in such a way that substrate cannot recognise it.
So,in competitive inhibition it competes with natural substrate for their attachment on the active sites of enzymes and it doesn't bind to allosteric site.

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Similar questions

Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.

Assertion (A) Competitive inhibitors compete with natural substrate for their attachment on the active sites of enzymes.
Reason (R) In competitive inhibition, inhibitor binds to the allosteric site of the enzyme.

Q. Assertion: Competitive inhibitors compete with the natural substrate for their attachment on the active sites of the enzyme.

Reason: In competitive inhibition, the inhibitor binds to the allosteric site of the enzyme.

Choose the correct option.

Assertion (A) Non-competitive inhibitor inhibits the catalytic activity of enzyme by binding with its active site.
Reason (R) Non-competitive inhibitor changes the shape of the active site in such a way that substrate can't recognise it.

Assertion (A) Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason (R) Drugs compete with natural substrate by attaching covalently to the active site of enzyme.

Q. Assertion: The compressibility factor for

H_{2}

and

H e

(1 + \frac{P b}{R T})

Reason: The compressibility factor for

H_{2}

and

H e

can be derived from Van der Waal's equation.

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