Assertion :Phenylketonuria is an inborn error of metabolism. Reason: Phenylalanine is not converted into alanine in individuals suffering from this disease.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.

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Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.

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Assertion is correct but Reason is incorrect.

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Both Assertion and Reason are incorrect.

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Solution

The correct option is C Assertion is correct but Reason is incorrect.
The genetic metabolic disorders in which the body is unable metabolize food into energy are called inborn errors of metabolism. They are usually caused by defective metabolic proteins (enzymes). Phenylketonuria is an inborn error of metabolism because the newborn is unable to properly break down the amino acid called phenylalanine. Hence, the assertion is correct. It is caused by absence of an enzyme called phenylalanine hydroxylase, which breaks down phenylalanine into tyrosine and not into alanine. Thus, reason is incorrect. Correct option is C.

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