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Question

During the processing of the prohormone "proinsulin" into the mature "insulin".

A
C-peptide is added to proinsulin
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B
C-peptide is removed from proinsulin
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C
B-peptide is added to proinsulin
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D
B-peptide is removed from proinsulin
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Solution

The correct option is B C-peptide is removed from proinsulin
Both C-Peptide and mature insulin are biologically active. Cell components and proteins in this image are not to scale. Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene.
So, the correct option is 'C-Peptide is removed from proinsulin'.

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