Question

Given below is a set of five terms. Rewrite the terms in correct order in a logical sequence.

Fibrin, Platelets, Thromboplastin, Fibrinogen, Thrombin

Answer 1

Blood coagulation

1. Blood coagulation is a process that converts elements of the blood into a gel, forming a blood clot and preventing loss of blood from injured blood vessels, tissues or organs.
2. Platelets play a key role in blood clotting.
3. Due to injury, platelets from the blood are attracted to the injured surface.
4. The platelets clump together to form an aggregate.
5. Following the tissue damage, extrinsic pathway is activated rapidly.
6. Damaged tissue releases a complex of chemicals called thromboplastin or tissue factor which initiates coagulation.
7. This results in the formation of prothrombin activator.
8. Prothrombin activates the enzyme thrombin, which converts inactive fibrinogen to soluble threads of fibrin.

Final answer: The correct order is: Platelets→ Thromboplastin→ Thrombin→ Fibrinogen→ Fibrin