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Question

______have been identified in normal human cells which, when activated under certain conditions, could transform normal cells into cancerous cells.

A
Oncogenes
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B
Proto oncogenes
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C
V-onc genes
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D
Both a and c
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Solution

The correct option is B Proto oncogenes

The cellular oncogenes (c-onc) or proto-oncogenes are present in the normal cells.

The proto-oncogene acts as a positive growth regulator, and is involved in promoting the differentiation and proliferation of normal cells.

However, these genes undergo mutations. The mutant, cancer-promoting forms of proto-oncogenes are referred to as oncogenes. This causes the transformation of normal cells to cancerous cells.

Viral oncogenes (v-onc) are present in oncogenic viruses that cause cancer. Example: Human papillomavirus.


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