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Question
If the father has autosomal dominant disease (heterozygous) and the mother is unaffected, then what will be the probability of having an affected offspring irrespective of the sex of the child?
[1 mark]
If the father has autosomal dominant disease (heterozygous) and the mother is unaffected, then what will be the probability of having an affected offspring irrespective of the sex of the child?
[1 mark]
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Solution
The correct option is D 50%
In autosomal (body chromosome) dominant disorder, the mutated gene is a dominant gene located on one of the autosomes, the chromosomes that play no role in sex determination.
Of the pair of genes present in the individual, the presence of a mutated gene in any one of the chromosomes is sufficient to affect the individual with this type of disorder.
A person with an autosomal dominant disorder, in this case, the father has a 50% chance of having an affected child with one mutated gene (dominant gene) and a 50% chance of having an unaffected child with two normal genes (recessive genes) irrespective of the sex of the child. Hence option d is correct.
In autosomal (body chromosome) dominant disorder, the mutated gene is a dominant gene located on one of the autosomes, the chromosomes that play no role in sex determination.
Of the pair of genes present in the individual, the presence of a mutated gene in any one of the chromosomes is sufficient to affect the individual with this type of disorder.
A person with an autosomal dominant disorder, in this case, the father has a 50% chance of having an affected child with one mutated gene (dominant gene) and a 50% chance of having an unaffected child with two normal genes (recessive genes) irrespective of the sex of the child. Hence option d is correct.
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