Question

If the sequence of bases in the coding strand of the transcription unit is 5'-ATTGATCGC-3', then find out the correct sequence of the mRNA transcribed from this transcription unit

• A. 3'-AUUGAUCGC-5'
• B. 5'-UAACTAGCC-3'
• C. 3'-AUUCATCGG-5'
• D. 5'-AUUGAUCGC-3'

Answer 1

The correct option is D 5'-AUUGAUCGC-3'

The genetic information from one strand of the DNA is copied into RNA during transcription. Hence, synthesis of RNA occurs during transcription.

The strand of DNA that has the polarity 3'→5' acts as a template, and is also referred to as a template strand.

The template strand of DNA serves in mRNA synthesis while the other strand that has the polarity 5'→3' is called a coding strand.

If the coding strand in a transcription unit has the following sequence: 5'-ATTGATCGC-3', then, it is known that the sequence of mRNA transcribed is the same as the coding strand of DNA. However, in RNA, thymine is replaced by uracil.
Hence, the sequence of mRNA will be 5'-AUUGAUCGC-3'