Major product in Friedel-Craft's acylation of anisole is:-

Chlorobenzene

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4-Chloro-1-methoxy benzene

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4-Methoxy-acetophenone

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3-Methoxy-acetophenone.

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Solution

The correct option is C 4-Methoxy-acetophenone
Friedel-Craft's acylation of anisole with acetyl chloride in presence of anhydrous $A l C l_{3}$ gives 4-methoxy acetophenone(para) as a major product. Methoxy group in anisole is activating and ortho-para directing with major product being para isomer.

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