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Question

Negative feedback occurs when

A
The rate of a process increases as the concentration of product increases.
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B
The rate of process decreases as the concentration of product decreases.
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C
The rate of process decreases as the concentration of product increases.
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D
The rate of a process increases as the concentration of product decreases.
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Solution

The correct option is C The rate of process decreases as the concentration of product increases.
  • A feedback mechanism for multistep reactions is a biological occurrence wherein the output of a system amplifies the system (positive feedback) or inhibits the system (negative feedback).
  • For example, Release of estrogen from the ovaries stimulates the secretion of GnRH from Hypothalamus which in turn stimulates the secretion of LH from anterior pituitary.when the levels of LH reaches above the normal levels in the blood it stimulates the release of progesterone from corpus luteum which causes the inhibition of the release of GnRH from the hypothalamus which in turn leads to inhibition of release of LH(product) from anterior pituitary and prevents the accumulation of LH(product)in blood. Hence negative feedback.
  • Hence Negative feedback occurs when The rate of process decreases as the concentration of product increases.
  • So, the correct answer is 'The rate of process decreases as the concentration of product increases'.

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