Question

Nobel Prize for one gene one enzyme hypothesis was given to

• A. Beadle and Tatum
• B. Watson and Crick
• C. Avery et al
• D. Sutton and Boveri

Answer 1

The correct option is A Beadle and Tatum

Watson and Crick
James Watson and Francis Crick along with MauriceWilkins received the Nobel Prize in $1962$ for their discovery of the molecular structure of DNA.

Sutton and Boveri
Sutton and Boveri proposed the chromosomal theory of inheritance in $1902$. They did not receive any Nobel prize for the same.

Avery et al
Avery, Mc Leod and McCarty proved through their experiment that the ‘transforming principle’ in Griffith’s experiment was DNA. They did not receive any Nobel prize for their discovery.

Beadle and Tatum
Beadle and Tatum irradiated Neurospora crassa with X-ray which resulted in mutant genes that could not synthesise the specific enzymes required for nutrition. Thus they proposed the one-gene-one-enzyme hypothesis in 1948 which states that each gene encodes a single enzyme.
They received the Nobel Prize for this discovery in $1958$.

Final answer
(D) Beadle and Tatum