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Introduction to Cell Mediated Immunity

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Question

Read the statements and choose the correct option.
I. Secretion of interferons is a physiological barrier of innate immunity.
II. T-lymphocytes are responsible for cell-mediated immunity.
III. Injection given against snake venom is a type of active immunization.
IV. Antibody produced during allergic reactions are of IgA type.

A

I and II alone are correct

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B

II and IV alone are correct

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C

I alone is correct

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D

II and III alone are correct

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E

II option is correct

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Solution

The correct option is E II option is correct
Cell-mediated immunity is an immune response that does not involve antibodies.
It involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.
Hence, T-lymphocytes are responsible for cell-mediated immunity.
So, the correct answer is 'II option is correct'.

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(i) It is only antibody that can cross placenta and confer immunity to foetus.

(ii) It is mediator in allergic reactions and activates histamine secreting cells.

(iii) It is the one that first activates in an initial attack of antigen.

(iv) It has role in activating and suppressing lymphocyte activity.

Q. Shot / Long answer type questions.
The barriers in the innate immunity are given in the following table. Identify a, b, C, and d.

	Type of barrier		Barrier
(i)	physical	(a)	skin
(ii)	physiological	(b)	in the eye
(iii)	tears	(c)	interferon
(iv)	cellular	(d)	WBC

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(ii) The cell-mediated immune response is responsible for the graft rejection.
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(iv) The acceptance or rejection of a kidney transplant depends on specific interferons.

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Q. Match the following column I and column II and choose the correct option.

	Column-I		Column-II
a.	Adaptive immune response	(i)	Neutrophils
b.	Associated with allergic reactions	(ii)	Lymphocytes
c.	Secrete serotonin and heparin	(iii)	Eosinophils
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Q. Read the statements (A - D) related to secondary immune response and select the correct option. (T-true and F-false)

A. Secondary immune response is slow and long lived.
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